Proteomics – The Pathway to Understanding and Decision-making in Medicine

Leaders in Pharmaceutical Business Intelligence (LPBI) Group

Larry H Bernstein, MD, FCAP, Author and Curator

http://pharmaceuticalintelligence.com/2014/06/22/Proteomics – The Pathway to Understanding and Decision-making in Medicine

This dialogue is a series of discussions introducing several perspective on proteomics discovery, an emerging scientific enterprise in the -OMICS- family of disciplines that aim to clarify many of the challenges toward the understanding of disease and aiding in the diagnosis as well as guiding treatment decisions. Beyond that focus, it will contribute to personalized medical treatment in facilitating the identification of treatment targets for the pharmaceutical industry. Despite enormous advances in genomics research over the last two decades, there is a still a problem in reaching anticipated goals for introducing new targeted treatments that has seen repeated failures in stage III of clinical trials, and even when success has been achieved, it is temporal.  The other problem has been toxicity of agents widely used in chemotherapy.  Even though the genomic approach…

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Is the Warburg Effect the Cause or the Effect of Cancer: A 21st Century View?

Is the Warburg Effect the Cause or the Effect of Cancer: A 21st Century View?.

Posted in allosterism, ATP production, cancer, carcinogenesis, computational biology, deacetylation, enzymology, fermentation, gene expression, glucose consumption, medicinal chemistry, mitochodria, nitric oxide synthase, oscillatory behavior, oxidative phosphorylation, oxidative stress, proteomics, RNA, ubiquitilation | Leave a comment

Garden Cress Extract Kills 97% of Breast Cancer Cells in Vitro

Garden Cress Extract Kills 97% of Breast Cancer Cells in Vitro.

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Moringa Oleifera Kills 97% of Pancreatic Cancer Cells in Vitro

Moringa Oleifera Kills 97% of Pancreatic Cancer Cells in Vitro.

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Targeting a key driver of cancer

Targeting a key driver of cancer.

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The Discovery and Properties of Avemar – Fermented Wheat Germ Extract: Carcinogenesis Suppressor

The Discovery and Properties of Avemar – Fermented Wheat Germ Extract: Carcinogenesis Suppressor.

Posted in cancer, carcinogenesis, fermentation, gene expression, mitochodria, nutritional factors, oxidative phosphorylation, oxidative stress, proteomics, RNA, ubiquitilation, Warburg effect, wheat germ extract | 2 Comments

Epilogue: Volume 4 – Post-Translational and Transformative Cardiology

Epilogue: Volume 4 – Post-Translational and Transformative Cardiology.

Posted in biomarkers, cardiovascular diseases, computational biology, gene expression, hypertension, mitochodria, oxidative stress, PTMs, s-nitrosylation, translational medicine, type 2 diabetes, ubiquitilation | Leave a comment

Summary – Part 2, Volume 4 – Translational Medicine in Cardiovascular Diseases

Summary – Part 2, Volume 4 – Translational Medicine in Cardiovascular Diseases.

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The Cancer Research Concentration @ Leaders in Pharmaceutical Business Intelligence

The Cancer Research Concentration @ Leaders in Pharmaceutical Business Intelligence.

Posted in allosterism, cancer, cancer biomarkers, cancer introduction, carcinogenesis, computational biology, enzymology, gene expression, mitochodria, nitric oxide, nitric oxide synthase, nutritional factors, oxidative phosphorylation, oxidative stress, proteomics, PTMs, ubiquitilation, Warburg effect | Leave a comment

Contents: Volume 4 – Part 2 Translational Medicine in CVD

Larry H Bernstein, MD, FCAP

http;//larryhdotme/WordPress.com/Contents_Volume 4_Part 2_Translational_ Medicine_in_CVD

Posted in cardiovascular diseases, endothelium, gene expression, hypertension, nitric oxide, nutritional factors, proteomics, PTMs, translational medicine, type 2 diabetes | Tagged , , , , , , , , | Leave a comment